MH1C1

Version 4.0.201701

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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105

This is the complete description of the cell line that you selected. By clicking on a generic term (e.g., SPECIES) you will go to the corresponding index (e.g., index of species), while by clicking on a specific term (e.g., retinoblastoma) you will go to the list of corresponding cell lines (e.g., retionoblastoma cell lines).

MH1C1 (rat, buffalo, liver, hepatoma)

Monoclonal continuous culture, grown as monolayer
epithelial morphology
SPECIES: rat, buffalo (male) Karyology: chromosome fragments and breaks
TISSUE/ORGAN: liver
TUMOR: hepatoma
tumorigenic in syngeneic animals
Susceptibility to viruses: herpes simplex * vaccinia * vesic. stomatitis (Indiana)
Cell line available under some conditions.
PROPERTIES: serum albumin prod.; serum complement components prod.; monooxygenases expression; tyrosine aminotransferase synthesis; enzymology; metabolism; toxicity screening; cytotoxicity; xenobiotic metabolism; hormone studies

Available in the following LABORATORY:

Istituto Patologia Generale, Universita' degli Studi (GEUCC, Genova)
Ham's F10 + 7.5% NBCS + 10 HS; Freezing medium: Culture medium + 10% DMSO; 37C, 5% CO2, split 1-5 Passage: 70, mycoplasma negative, HOECHST
Chromosome markers: 1 large chromosome with submedian centromere; 1-2 large chromosomes with median centromeres. Derived from hepatoma induced by N-2-fluorenylpthalamic acid.
Validated by: monooxygenase expression and induction

Availability in cell line catalogues: ATCC: CCL 144, ECACC: 85112702, DSMZ: ACC 106, ICLC: ATL98014

Bibliographic references:

Cell Biochem Funct 1988;6:245-250 - PMID: 3191583
Chem Biol Interact 1988;65:629-634
Exp Cell Res 1991;196:330-336 - PMID: 1716586
In Vitro 1970;6:32 - PMID: 4399803
J Cell Biol 1969;40:236-247 - PMID: 4177659
J Cell Res 1969;40:236
Science 1970;170:533 - PMID: 4908238

See homonymous cell lines in other collections and catalogues.

For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105