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Entry from: Somatic Mutations Prevalence data set (Rel. 14)
 
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TP53_PREVALENCE
Prevalence_id 216
Topography LIVER AND INTRAHEPATIC BILE DUCTS
Topo_code C22
Morphology Hepatocellular carcinoma, NOS (C22.0)
Morpho_code 8170/3
Sample_analyzed 16
Sample_mutated 8
Population Eastern Asia
Country China
Comment Patients from high AFB1 exposure area
Ref_id 15
Cross_ref_id -
Title Mutational hotspot in the p53 gene in human hepatocellular carcinomas
Authors Hsu IC;Metcalf RA;Sun T;Welsh JA;Wang NJ;Harris CC;
Year 1991
Journal Nature
Volume 350
Start_page 427
End_page 428
PubMed_entry 1849234
Ref_comment -
Tissue_processing fixed
Start_material DNA
Prescreening none
Material_sequenced direct
Exon2 No
Exon3 No
Exon4 No
Exon5 Yes
Exon6 Yes
Exon7 Yes
Exon8 Yes
Exon9 No
Exon10 No
Exon11 No
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