SPECIES: human
TISSUE/ORGAN: blood
TUMOR: lymphoma, Burkitt
ECACC catalog code: 87060801
Morphology: Lymphoblast
Description: Human Burkitt's Lymphoma
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: This material is cited in a US and/or other Patent and may not be used to infringe patent claims.
Properties: Products: Immunoglobulin M (IgM), lambda Applications: Interferon studies
Available in the following LABORATORY:
-
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C. A maximum density of 2x1,000,000 cells/ml is possible.
Karyotype: Modal No. 44; hypodiploid
Secretes small amounts of an IgM monoclonal antibody of unknown specificity. It has been used for commercial production of human interferon. The cells contain the EBV genome and should be handled under laboratory containment level 2.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ATCC: CRL 1432, IZSBS: BS TCL 47, DSMZ: ACC 24
Bibliographic references:
- Antimicrob Agents Chemother 1979;15:420 - PMID: 465469
- Cancer 1969;23:64-79 - PMID: 4178827
- Dev Biol Stand 1978;38:343
- Int J Cancer 1972;10:44 - PMID: 4122458
- Int J Cancer 1973;12:396 - PMID: 4365093
- J Gen Virol 1982;63:207 - PMID: 7175502
IZSBS catalog code: BS TCL 47
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (child) Karyology: unknown
TUMOR: lymphoma, Burkitt
DEPOSITOR: obtained from ATCC
PROPERTIES: interferon alpha prod.; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CRL 1432, ECACC: 87060801, DSMZ: ACC 24
Bibliographic references:
- Dev Biol Stand 1978;38:343
- Int J Cancer 1973;12:396 - PMID: 4365093
- J Gen Virol 1982;63:207 - PMID: 7175502
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (child)
TUMOR: lymphoma, Burkitt
PROPERTIES: IgM prod.; interferon alpha prod.; interferon; c-myc mRNA expression; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CRL 1432, IZSBS: BS TCL 47, ECACC: 87060801, DSMZ: ACC 24
Bibliographic references:
- Antimicrob Agents Chemother 1979;15:420 - PMID: 465469
- Cancer 1969;23:64-79 - PMID: 4178827
- Dev Biol Stand 1978;38:343
- Int J Cancer 1972;10:44 - PMID: 4122458
- Int J Cancer 1973;12:396 - PMID: 4365093
- J Gen Virol 1982;63:207 - PMID: 7175502
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (child)
TUMOR: lymphoma, Burkitt
PROPERTIES: IgM prod.; interferon alpha prod.; interferon; c-myc mRNA expression; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CRL 1432, IZSBS: BS TCL 47, ECACC: 87060801, DSMZ: ACC 24
Bibliographic references:
- Antimicrob Agents Chemother 1979;15:420 - PMID: 465469
- Cancer 1969;23:64-79 - PMID: 4178827
- Dev Biol Stand 1978;38:343
- Int J Cancer 1972;10:44 - PMID: 4122458
- Int J Cancer 1973;12:396 - PMID: 4365093
- J Gen Virol 1982;63:207 - PMID: 7175502
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it
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If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730;
PMID: 18927105
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