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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
Cell line available under some conditions.
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)


SPECIES: human
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic

ECACC catalog code: 85011413
Morphology: Suspension
Susceptibility to viruses: alpha viruses * measles
Description: Human acute T lymphoblastic leukaemia
Viruses: See Properties
Depositor: Prof H Harris/Dr R Sutherland, Sir William Dunn School of Pathology, Oxford, UK
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Tumourigenicity studies

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Monoclonal continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, peripheral blood, leukemia, T cell)

ICLC catalog code: HTL99025
Continuous culture, grown as suspension
round cells, single or in clumps, lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, T cell
DEPOSITOR: Dr G. Canti, Pharmacology Dept, Milan, Italy
Cell line available for distribution. For non-commercial investigative use only
PROPERTIES: G->A mutation at codon 248 of the p53; CD1+ CD2+ CD3+ CD4+ CD5+ CD6+ CD7+ CD19- EBV-; high level of terminal deoxynucleotidyl transferase

Available in the following LABORATORY:

Availability in cell line catalogues: ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, peripheral blood, leukemia)

IZSBS catalog code: BS TCL 85
Continuous culture, grown as suspension
Lymphoblast-like morphology
SPECIES: human
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia
DEPOSITOR: obtained from ATCC
Distribution is subjected to authorization by the assignee.
Patent strain

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL-1582, ICLC: HTL99025, ECACC: 85011413, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Monoclonal continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:


MOLT-4 (human, lymphocyte, T, leukemia, acute lymphoblastic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human (male, 19 years old)
TISSUE/ORGAN: lymphocyte, T
TUMOR: leukemia, acute lymphoblastic
tumorigenic in nude mice
Susceptibility to viruses: alpha viruses * measles
PROPERTIES: antigen presentation; biochemical markers; antitumour testing; biochemistry; immunology; tumor cytotoxicity; tumorigenicity; differentiation; target line; cytotoxicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1582, ICLC: HTL99025, ECACC: 85011413, IZSBS: BS TCL 85, DSMZ: ACC 362

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105