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SPECIES: human, Caucasian
TISSUE/ORGAN: pleural effusion
TUMOR: lymphoma, histiocytic
ECACC catalog code: 85011440
Susceptibility to viruses: HIV-1 * HIV-2
Description: Human Caucasian histiocytic lymphoma
Viruses: See Properties
Depositor: Prof H Harris/Dr R Sutherland, Sir William Dunn School of Pathology, Oxford, UK
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Tumourigenicity studies
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 2-9x100,000 cells/ml; 5% CO2; 37C.
Derived from malignant cells of a pleural effusion of 37 year old caucasian male with diffuse histiocytic lymphoma. One of only a few human lines still expressing many of the monocytic like characteristics exhibited by cells of histiocytic origin.
Research council deposit: No;
Price Code: A;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ATCC: CRL 1593
- Int J Cancer 1976;17:565-577 - PMID: 178611
- J Exp Med 1976;143:1528-1533 - PMID: 1083890
- J Immunol 1980;125:463-465 - PMID: 7381208
- Nature 1979;279:328-331 - PMID: 450085
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.