McA-RH7777's homonymous lines

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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105

McA-RH7777 (rat, buffalo, liver, hepatoma)

Monoclonal continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: rat, buffalo (female)
TISSUE/ORGAN: liver
TUMOR: hepatoma
tumorigenic and metastatic in syngeneic animals
Cell line available under some conditions.
PROPERTIES: albumin prod.; fetoprotein alpha prod.; steroid hormones sensitive; tumorigenicity; toxicity screening; cytotoxicity; xenobiotic metabolism

Available in the following LABORATORY:

Istituto Patologia Generale, Universita' degli Studi (GEUCC, Genova)
Swim's S77 medium + 20% HS + 5% FBS + 2mM L-Glutamine; Freezing medium: Culture medium + 10% DMSO; 37C, 5% CO2, split 1-6 , mycoplasma positive, HOECHST
Validated by: monooxygenase expression and induction

Availability in cell line catalogues: ATCC: CRL 1601, ICLC: ATL00002

Bibliographic references:

J Biol Chem 1982;257:5827 - PMID: 6175632
Onco-Developmental Gene Expression (Fishman and Sell ed, Academic Press N Y) 1976;259-270
Recent Results Cancer Res 1974;44:103

McA-RH7777 (rat, buffalo, liver, hepatoma)

Continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: rat, buffalo (female)
TISSUE/ORGAN: liver
TUMOR: hepatoma
tumorigenic and metastatic in syngeneic animals
PROPERTIES: albumin prod.; fetoprotein alpha prod.; steroid hormones sensitive; tumorigenicity; toxicity screening; cytotoxicity; xenobiotic metabolism

Available in the following LABORATORY:

Russian Academy of Medical Sciences (MWIIW, Moscow)
mycoplasma negative

Availability in cell line catalogues: ATCC: CRL 1601, ICLC: ATL00002

Bibliographic references:

J Biol Chem 1982;257:5827 - PMID: 6175632
Onco-Developmental Gene Expression (Fishman and Sell ed, Academic Press N Y) 1976;259-270
Recent Results Cancer Res 1974;44:103

For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105