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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


KB (human, Caucasian, cervix, carcinoma)


SPECIES: human, Caucasian
TISSUE/ORGAN: cervix
TUMOR: carcinoma

DSMZ catalog code: ACC 136
Morphology: adherent cells, epithelial-like, growing as monolayers
Susceptibility to viruses: adenovirus 3 * herpes simplex * influenza * poliovirus 1 * vaccinia
Description: human cervix carcinoma (derivative of HELA) originally described as 'epidermoid carcinoma established from the mouth of a Caucasian man in 1954'; however, as shown by DSMZ DNA fingerprinting (see below) this cell line must be considered an HELA subclone (human cervix carcinoma, see HELA DSM ACC 57) confirmed as human with IEF of AST, MDH
Viruses: ELISA: reverse transcriptase negative; PCR: EBV-, HBV-, HCV-, HIV-, HTLV-I/II-
Depositor: Dr. J. Wehland, GBF, Braunschweig, Germany
General Restrictions

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 17, IZSBS: BS TCL34, ECACC: 94050408

Bibliographic references:


KB (human, Caucasian, mouth, carcinoma, epidermoid)


SPECIES: human, Caucasian
TISSUE/ORGAN: mouth
TUMOR: carcinoma, epidermoid

ECACC catalog code: 94050408
Morphology: Epithelial-like
Susceptibility to viruses: adenovirus 3 * herpes simplex * influenza * poliovirus 1 * vaccinia
Description: Human oral epidermoid carcinoma, HeLa characteristics
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: None Specified By Depositor
Properties: Applications: KB has been used extensively in studies of cell nutrition and metabolism, cancer chemotherapy screening, tumourigenicity and viruses e.g. susceptible to Polio virus type I and Adenovirus type 3.

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 17, IZSBS: BS TCL34, DSMZ: ACC 136

Bibliographic references:


KB (human, Caucasian, mouth, carcinoma, squamous cell)

IZSBS catalog code: BS TCL34
Continuous culture, grown as monolayer
epithelial morphology
SPECIES: human, Caucasian (male, Adult) Karyology: modal number 74-78
TISSUE/ORGAN: mouth
TUMOR: carcinoma, squamous cell
Susceptibility to viruses: adenovirus 3 * herpes simplex * influenza * poliovirus 1 * vaccinia
PROPERTIES: nutrition; metabolism; chemotherapeutic agents; tumorigenicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 17, ECACC: 94050408, DSMZ: ACC 136


KB (human, Caucasian, mouth, carcinoma, squamous cell)

Continuous culture, grown as monolayer
epithelial morphology
SPECIES: human, Caucasian (male, Adult) Karyology: modal number 74-78
TISSUE/ORGAN: mouth
TUMOR: carcinoma, squamous cell
Susceptibility to viruses: adenovirus 3 * herpes simplex * influenza * poliovirus 1 * vaccinia
PROPERTIES: nutrition; metabolism; chemotherapeutic agents; tumorigenicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 17, IZSBS: BS TCL34, ECACC: 94050408, DSMZ: ACC 136

Bibliographic references:


KB (human, Caucasian, mouth, carcinoma, squamous cell)

Continuous culture, grown as monolayer
epithelial morphology
SPECIES: human, Caucasian (male, Adult) Karyology: modal number 74-78
TISSUE/ORGAN: mouth
TUMOR: carcinoma, squamous cell
Susceptibility to viruses: adenovirus 3 * herpes simplex * influenza * poliovirus 1 * vaccinia
PROPERTIES: nutrition; metabolism; chemotherapeutic agents; tumorigenicity; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 17, IZSBS: BS TCL34, ECACC: 94050408, DSMZ: ACC 136

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105