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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, DSMZ: ACC 3, ICLC: HTL95010

Bibliographic references:


HL-60 (human, peripheral blood, leukemia, acute myeloid)


SPECIES: human
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, acute myeloid

DSMZ catalog code: ACC 3
Morphology: round, single cells in suspension
Susceptibility to viruses: HIV-1 * HTLV-1
Description: human acute myeloid leukemia established from the peripheral blood of a 35-year-old woman with acute myeloid leukemia (AML FAB M2) in 1976; cells can be used for induction of differentiation studies; described to be responsive to DMSO, phorbol ester TPA and other reagents and to carry amplified c-myc gene; present cells are apparently tetraploid derivates of hypodiploid original where c-myc was amplified in dmin (instead of hsr) confirmed as human with IEF of MDH, NP
Viruses: ELISA: reverse transcriptase negative; PCR: EBV-, HBV-, HCV-, HHV-8-, HIV-, HTLV-I/II-
Depositor: Dr. E. Porfiri, The Royal Free Hospital, Department of Haematology, London, UK
General Restrictions

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, ICLC: HTL95010

Bibliographic references:


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

ICLC catalog code: HTL95010
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
DEPOSITOR: Obtained from ECACC.
Cell line available for distribution. For non-commercial investigative use only
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: DSMZ: ACC 3

Bibliographic references:


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, DSMZ: ACC 3, ICLC: HTL95010

Bibliographic references:


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, DSMZ: ACC 3, ICLC: HTL95010

Bibliographic references:


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, DSMZ: ACC 3, ICLC: HTL95010

Bibliographic references:


HL-60 (human, Caucasian, peripheral blood, leukemia, promyelocytic)

Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Caucasian (female, 36 years old) Karyology: pseudodiploid
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, promyelocytic
tumorigenic in nude mice
Susceptibility to viruses: HIV-1 * HTLV-1
PROPERTIES: phagocytosis; antitumour testing; differentiation; pharmacodynamics; cloning

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 240, DSMZ: ACC 3, ICLC: HTL95010

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105