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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


HeLa (human, Black, cervix, carcinoma, epitheloid)


SPECIES: human, Black
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid

DSMZ catalog code: ACC 57
Morphology: epithelial-like cells growing in monolayers
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
Description: human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951; later diagnosis changed to adenocarcinoma; first aneuploid, continuously cultured human cell line confirmed as human with IEF of G6PD, MDH, NP
Viruses: ELISA: reverse transcriptase negative; PCR: EBV-, HBV-, HCV-, HHV-8-, HIV-, HTLV-I/II-
Depositor: obtained from ATCC (CCL 2), Rockville, Maryland, USA
General Restrictions

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, IZSBS: BS TCL20, ECACC: 93021013, ICLC: HTL95023

Bibliographic references:


HeLa (human, Black, cervix, carcinoma, epitheloid)


SPECIES: human, Black
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid

ECACC catalog code: 93021013
Morphology: Epithelial
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
Description: Human Negroid cervix epitheloid carcinoma
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Virus studies

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, IZSBS: BS TCL20, DSMZ: ACC 57, ICLC: HTL95023

Bibliographic references:


HeLa (human, Black, cervix, carcinoma, epitheloid)

ICLC catalog code: HTL95023
Continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: human, Black (female, 31 years old) Karyology: aneuploid
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid
tumorigenic in nude mice
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
DEPOSITOR: Obtained from ECACC
Cell line available for distribution. For non-commercial investigative use only
PROPERTIES: antitumour testing; transformation; tumorigenicity; cytotoxicity; bacterial invasiveness; virology

Available in the following LABORATORY:

Availability in cell line catalogues: IZSBS: BS TCL20, ECACC: 93021013, DSMZ: ACC 57

Bibliographic references:


HeLa (human, Black, cervix, carcinoma, epitheloid)

IZSBS catalog code: BS TCL20
Continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: human, Black (female, 31 years old) Karyology: aneuploid
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid
tumorigenic in nude mice
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
PROPERTIES: antitumour testing; transformation; tumorigenicity; cytotoxicity; cell biology; bacterial invasiveness; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, ECACC: 93021013, DSMZ: ACC 57, ICLC: HTL95023


HeLa (human, Black, cervix, carcinoma, epitheloid)

Continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: human, Black (female, 31 years old) Karyology: aneuploid
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid
tumorigenic in nude mice
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
PROPERTIES: antitumour testing; transformation; tumorigenicity; cytotoxicity; cell biology; bacterial invasiveness; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, IZSBS: BS TCL20, ECACC: 93021013, DSMZ: ACC 57, ICLC: HTL95023

Bibliographic references:


HeLa (human, Black, cervix, carcinoma, epitheloid)

Continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: human, Black (female, 31 years old) Karyology: aneuploid
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid
tumorigenic in nude mice
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
PROPERTIES: antitumour testing; transformation; tumorigenicity; cytotoxicity; cell biology; bacterial invasiveness; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, IZSBS: BS TCL20, ECACC: 93021013, DSMZ: ACC 57, ICLC: HTL95023

Bibliographic references:


HeLa (human, Black, cervix, carcinoma, epitheloid)

Monoclonal continuous culture, grown as monolayer
epithelial-like morphology
SPECIES: human, Black (female, 31 years old) Karyology: aneuploid
TISSUE/ORGAN: cervix
TUMOR: carcinoma, epitheloid
tumorigenic in nude mice
Susceptibility to viruses: adenovirus 3 * arbovirus * Coxsackie * echovirus * measles * poliovirus 1 * reovirus 3 * respiratory syncytial virus * rhinovirus * vaccinia
PROPERTIES: antitumour testing; transformation; tumorigenicity; cytotoxicity; cell biology; bacterial invasiveness; virology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CCL 2, IZSBS: BS TCL20, ECACC: 93021013, DSMZ: ACC 57, ICLC: HTL95023

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105