ECACC catalog code: 94060902
Description: Human thyroid carcinoma
Viruses: See Properties
Depositor: Dr J Köhrle, Klinische Forschergruppe, Medizinische Poliklinik, Würzburg, GERMANY
No restrictions. Patent: None Specified By Depositor
Properties: Products: Expression of 5' - Deiodinase Type I Applications: Function of human thyroid and development of thyroid cancer.
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
DMEM:Ham's F12 (1:1) + 2mM Glutamine + 5% Fetal Bovine Serum (FBS). Split confluent cultures 1:10 to 1:20 i.e. seeding at 1-4x10,000 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37C.
FTC-238 was established from a lung metastasis of a follicular thyroid carcinoma from a 42-year-old male. The cells are polymorphic showing flat polygonal to spindle-like morphologies. Complex chromosomal changes were detected as well as a p53 mutation.
Research council deposit: No;
Price Code: C;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ICLC: HTL96003
- Cancer Res 1990;118:48 - PMID: 2152773
- Front Horm Res 1989;18:56
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If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.