MTC SK

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For information, get in touch with: Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105

This is the complete description of the cell line that you selected. By clicking on a generic term (e.g., SPECIES) you will go to the corresponding index (e.g., index of species), while by clicking on a specific term (e.g., retinoblastoma) you will go to the list of corresponding cell lines (e.g., retionoblastoma cell lines).

MTC SK (human, thyroid, medullary, carcinoma)

SPECIES: human
TISSUE/ORGAN: thyroid, medullary
TUMOR: carcinoma

ECACC catalog code: 92013101
Morphology: Spherical, cells grow in large clusters
Description: Human medullary thyroid carcinoma
Viruses: See Properties
Depositor: Dr R Pfragner, Karl-Franzens University, Graz, AUSTRIA (Originator)
Restricted. Patent: None Specified By Depositor
Properties: Products: Peptides eg calcitonin, calcitonin-gene related peptide, gastric-releasing peptide, somatostatin Applications: Neuroendocrinology, cytogenetics, MEN2-syndrome

Available in the following LABORATORY:

Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
Ham's F12 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-5x100,000 cells/ml; 5% CO2; 37C.
Passages: 106; Originated from C-cells of the thyroid gland known to produce several peptides including serotonin. The loose attachment of the cells corresponds to the lack of cellular junctions.
Research council deposit: No; Price Code: C;
Validated by: isoenzymes (species confirmation)

Bibliographic references:

Cancer Res 1990;50:4160-4166 - PMID: 1972348

For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Paola Visconti
Email: paola.visconti@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105