1. Chiappori F, Ferrario MG, Gaiji N, Fantucci P
Docking of estrogen and genistein like molecular library on Estrogen Receptor alpha and beta
Meeting: BITS 2005 - Year: 2005
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Abstract: Estrogen replacement therapy is one of the most efficient treatment of menopausal symptoms. Unfortunately, despite the benefits of estrogenic therapy evidence exists of increasing number of cases of reproductive tissue cancer. This lead to a strong interest in discovering new compounds that display the benefits of estrogens avoiding such risks. We decided to apply a virtual high throughput screening, based on docking simulations, for the identification of new possible selective receptor compounds.