BITS Meetings' Virtual Library:
Abstracts from Italian Bioinformatics Meetings from 1999 to 2013

766 abstracts overall from 11 distinct proceedings

1. Punta M, Rost B
PROFcon: prediction of internal protein contacts
Meeting: BITS 2005 - Year: 2005
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Topic: Structural Bioinformatics

Abstract: Novel and more efficient structural prediction methods are needed in order to reduce the everincreasing gap between the number of known protein sequences and structures. Better predictions of non-local contacts between residues could help improve fold recognition and de novo modeling. In the present study, we introduce PROFcon, a novel contact prediction method based on a neural network that combines information from various sources. PROFcon predictions are then used to estimate experimental folding rates of two-state proteins (i.e. proteins that fold without intermediate states).

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