BITS Meetings' Virtual Library:
Abstracts from Italian Bioinformatics Meetings from 1999 to 2013

766 abstracts overall from 11 distinct proceedings

1. Menozzi G, Riva L, Sironi M, Pozzoli U
Intron and exon lengths influence on splicing
Meeting: BITS 2004 - Year: 2004
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Topic: Unspecified

Abstract: Splice site consensus values (CVs) are usually calculated using previously described matrices [1] which are obtained through the analysis of a relatively small splice site number (1500) from different organisms. Now, genome annotation becoming complete, a much more accurate definition is possible. Furthermore, recent studies [2, 3, 4] indicate that consensus value itself is not sufficient to define splice site strength and other parameters must be considered to improve splice site definition. To investigate how intron and exon lengths might be exploited by the splicing machinery to ensure proper splicing control and regulation a human intron database has been developed and analyzed.

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