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For information, get in touch with: Dott.ssa Barbara Parodi
Email: barbara.parodi@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


THP-1 (human, peripheral blood, leukemia, acute monocytic)


SPECIES: human
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, acute monocytic

DSMZ catalog code: ACC 16
Morphology: round, single cells in suspension, partly in clusters
Susceptibility to viruses: HIV-1
Description: human acute monocytic leukemia established from the peripheral blood of a 1-year-old boy with acute monocytic leukemia (AML) at relapse in 1978; the cells can be used for induction of differentiation studies; the cells were described to produce lysozyme and to be phagocytic confirmed as human with IEF of AST, MDH, NP
Viruses: ELISA: reverse transcriptase negative; PCR: EBV-, HBV-, HCV-, HHV-8-, HIV-, HTLV-I/II-
Depositor: Dr. J. Minowada, Fujisaki Cell Center, Okayama, Japan
General Restrictions

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: TIB 202, ICLC: HTL97014

Bibliographic references:


THP-1 (human, peripheral blood, leukemia, acute monocytic)

Continuous culture, grown as suspension
large, round, single cells morphology
SPECIES: human (male, 1 years old)
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, acute monocytic
Susceptibility to viruses: HIV-1
PROPERTIES: differentiation; lysozyme synthesis; phagocytosis; Fc receptor; IL-1 prod.; C3b receptor

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: TIB 202, DSMZ: ACC 16, ICLC: HTL97014

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
Email: barbara.parodi@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105