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For information, get in touch with: Dott.ssa Barbara Parodi
Email: barbara.parodi@hsanmartino.it
  P. Romano, A. Manniello et al. Nucl Acids Res 2009 37:D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105


PC-12 (rat, New England Deaconess Hospital strain, adrenal medulla, pheochromocytoma)


SPECIES: rat, New England Deaconess Hospital strain
TISSUE/ORGAN: adrenal medulla
TUMOR: pheochromocytoma

ECACC catalog code: 88022401
Morphology: With collagen - neuronal fibroblasts; without collagen - spherical clusters
Description: Rat adrenal phaeochromocytoma
Depositor: Obtained from ATCC, USA

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1721, DSMZ: ACC 159, ICLC: ATL98004, IZSBS: BS TCL 91

Bibliographic references:


PC-12 (rat, adrenal, pheochromocytoma)

ICLC catalog code: ATL98004
Continuous culture, grown as suspension
clusters of small cells morphology
SPECIES: rat
TISSUE/ORGAN: adrenal
TUMOR: pheochromocytoma
DEPOSITOR: Dr T. Florio, Neuroscience Unit, ABC, Genoa, Italy
Cell line available for distribution upon consent of the depositor. For non-commercial investigative use only
PROPERTIES: the cells are described to synthesize catecholamines (dopamine, norepinephrine); respond reversibly to NGF by induction of the neuronal phenotype.

Available in the following LABORATORY:

Availability in cell line catalogues: ECACC: 88022401, DSMZ: ACC 159, IZSBS: BS TCL 91

Bibliographic references:


PC-12 (rat, adrenal medulla, pheochromocytoma)

IZSBS catalog code: BS TCL 91
Continuous culture, grown as monolayer
Neuron-like morphology
SPECIES: rat
TISSUE/ORGAN: adrenal medulla
TUMOR: pheochromocytoma
DEPOSITOR: obtained from ATCC
PROPERTIES: these cells may be useful model systems for neurobiological and neurochemical studies; expressing xenobiotic metabolizing enzymes; respond reversibly to nerve growth factor

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL-1721, ECACC: 88022401, DSMZ: ACC 159, ICLC: ATL98004

Bibliographic references:


PC-12 (rat, New England Deaconess Hospital strain, adrenal medulla, pheochromocytoma)

Monoclonal continuous culture, grown as monolayer
chromaffin cells morphology
SPECIES: rat, New England Deaconess Hospital strain
TISSUE/ORGAN: adrenal medulla
TUMOR: pheochromocytoma
tumorigenic in syngeneic animals
PROPERTIES: catecholamine prod.; neurotransmitter prod.; NPP prod.; dopamine prod.; differentiation; neurobiochemistry; neurobiology

Available in the following LABORATORY:

Availability in cell line catalogues: ATCC: CRL 1721, ECACC: 88022401, DSMZ: ACC 159, ICLC: ATL98004, IZSBS: BS TCL 91

Bibliographic references:



For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
Email: barbara.parodi@hsanmartino.it

If you want to cite CLDB and HyperCLDB, please use the following reference:

P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.
DOI: doi:10.1093/nar/gkn730; PMID: 18927105