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TISSUE/ORGAN: lymph node
TUMOR: carcinoma, small cell
ECACC catalog code: 96020717
Morphology: Floating aggregates
Description: Human lung small cell carcinoma
Viruses: See Properties
Depositor: Dr P Twentyman, UKCCCR, Lincolns Inn Fields, London, UK (Originator)
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Cytotoxicity studies, study of small cell lung cancer
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
The cell line COR-L24 was established from a lymph node biopsy of an untreated 71 year-old male and was diagnosed as small cell lung carcinoma (SCLC). Bone marrow taken from the same patient contained hypercellular marrow consistent with normal haemopoietic cells and no evidence of neoplasm. In culture, this xenograft forming cell line grows as floating aggregates of packed cells with irregular shape. Cell line COR-L103 (96020735) was established from the same patient, having been isolated after treatment.
Research council deposit: Yes;
Price Code: C;
Validated by: isoenzymes (species confirmation)
- Br J Cancer 1985;52:495 - PMID: 2998422
- Cancer Res 1992;52:5674 - PMID: 1327513
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.