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SPECIES: human, Caucasian
TISSUE/ORGAN: peripheral blood
TUMOR: leukemia, acute lymphoblastic
ECACC catalog code: 85112105
Susceptibility to viruses: HIV-1 * HIV-2 * HTLV-1
Description: Human Caucasian acute lymphoblastic leukaemia
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: None Specified By Depositor
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 20% Fetal Bovine Serum (FBS). Maintain cultures between 2-3x100,000 cells/ml; 5% CO2; 37C. Maximum cell density 1-2x1,000,000 cells/ml.
Karyotype: 2n = 46
A T lymphoblastoid line obtained from the peripheral blood of a 4 year old Caucasian female with acute lymphoblastoid leukaemia. These may be grown to a high density in a spinner type suspension culture. Cells are reported to be free of virus particles as determined by electron microscopy.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ATCC: CCL 119, IZSBS: BS TCL11, DSMZ: ACC 240
- Cancer 1965;18:522-529
- Cancer 1966;19:1725 - PMID: 5224274
- Exp Cell Res 1965;40:197 - PMID: 5318974
See homonymous cell lines in other collections and catalogues.
For information, get in touch with:
IRCCS AOU San Martino IST,
c/o Centro Biotecnologie Avanzate, Torre D - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Assunta Manniello
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.