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TUMOR: leukemia, T cell
ECACC catalog code: 88051601
Description: Human T cell leukaemia
Viruses: See Properties
Depositor: Dr J Clarke, CAMR, Porton Down, Salisbury, UK
No restrictions. Patent: None Specified By Depositor
Properties: Products: Human T Lymphotrohpic Virus 1 (HTLV-1) tat gene Applications: Virus studies: support growth of HIV
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
Clone of C63/CRII-4 derived by fusion of primary umbilical cord blood cells with HTLV-1 producing line from adult T cell leukaemia lymphoma patient. Contain defective HTLV-1 genome. In presence of HIV cells fuse to form syncytia. The cells should be handled under laboratory containment level 2.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
- Nature 1983;303:253 - PMID: 6341859
- Science 1984;381 - PMID: 6330891
- Virology 1983;129:51 - PMID: 6412453
- Virology 1987;158:44 - PMID: 3107214
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.