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IZSBS catalog code: TCL 130
Continuous culture, grown as monolayer
SPECIES: rat Karyology: unknown
TISSUE/ORGAN: thyroid, medullary
DEPOSITOR: obtained from ATCC
PROPERTIES: secreting peptides (neurotensin and calcitonin)
Available in the following LABORATORY:
- Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSBS, Brescia)
DMEM (4.5 g/l glucose) + 10% HS ; Freezing medium: Culture medium + 10% DMSO; 37C, 5% CO2, mycoplasma negative, culture
It is of C-cell origin derived from the non-clonal line rMTC 6-23; producing neurotensin and calcitonin after stimulation by calcium, KCl, glucagon and catecholamines. Cell adhesion must be improved by using flasks coated with collagen type IV.
Availability in cell line catalogues: ATCC: CRL-1607, ECACC: 87042206
- Endocrinology 1980;107:509-516 - PMID: 6248326
- Proc Natl Acad Sci U S A 1980;77:3741-3745 - PMID: 6932046
See homonymous cell lines in other collections and catalogues.
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.