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SPECIES: mouse, BALB/c
ECACC catalog code: 91031103
Susceptibility to viruses: vesic. stomatitis (Indiana)
Description: Mouse BALB/c myeloma
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: None Specified By Depositor
Properties: Products: Immunoglobulin G (IgG2b), half molecules, light chain dimers, free light chains Applications: Tumourigenicity studies
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
DMEM + 2mM Glutamine + 20% Horse Serum (HS). Maintain cultures between 2-9x100,000 cells/ml; 5% CO2; 37C.
Karyotype: Modal No. 67-70
Established from the Merwin plasma cell tumour-II carried in BALB/c mice. Resembles the parent tumour in that they both produced fully assembled gamma globulin molecules (Ig G2b) as well as half molecules, light chain dimers and free light chains. The MPC-II produces 5-6 picograms of IgG2b per cell per minute.
Research council deposit: No;
Price Code: C;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ATCC: CCL 167, IZSBS: BS TCL45
- J Exp Med 1970;131:515 - PMID: 4189836
- J Mol Biol 1971;56:327 - PMID: 5102530
- Science 1970;167:186 - PMID: 4188146
See homonymous cell lines in other collections and catalogues.
For information, get in touch with:
IRCCS Ospedale Policlinico San Martino
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Barbara Parodi
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.