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TISSUE/ORGAN: peripheral blood
TUMOR: lymphoma, cutaneous, T cell
ECACC catalog code: 88041901
Susceptibility to viruses: HIV * HTLV-1 * siv mac 251
Description: Human T cell lymphoma
Viruses: See Properties
Depositor: Dr G Farrar, PHLS CAMR, Porton Down, Salisbury, USA
No restrictions. Patent: None Specified By Depositor
Properties: Products: Interleukin 2 (IL-2)
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
Derived from peripheral blood of a 50 year old male patient with Sezary syndrome. Cells exhibit the features of a mature T cell line with inducer/helper phenotype. Biologically active IL-2 can be eluted from the cell surface.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
Availability in cell line catalogues: ATCC: TIB 161
- Blood 1980;55:409-417 - PMID: 6244013
- J Biol Chem 1959;234:1042
- J Exp Med 1981;154:1403-1418 - PMID: 6975346
For information, get in touch with:
IRCCS AOU San Martino IST,
c/o Centro Biotecnologie Avanzate, Torre D - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Dott.ssa Assunta Manniello
If you want to cite CLDB and HyperCLDB, please use the following reference:
P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi.
Cell Line Data Base: structure and recent improvements towards molecular authentication of human cell lines.
Nucleic Acids Research 2009 37(Database issue):D925-D932.